Deep-inspiration breath-hold PET/CT: clinical findings with a new technique for detection and characterization of thoracic lesions.
نویسندگان
چکیده
UNLABELLED Respiratory motion during PET/CT acquisition can cause misregistration and inaccuracies in calculation of standardized uptake values (SUVs). Our aim was to compare the detection and characterization of thoracic lesions on PET/CT with and without a deep-inspiration protocol. METHODS We studied 15 patients with suspected pulmonary lesions who underwent clinical PET/CT, followed by deep-inspiration breath-hold (BH) PET/CT. In BH CT, the whole chest of the patient was scanned in 15 s at the end of deep inspiration. For BH PET, patients were asked to hold their breath 9 times for 20-s intervals. One radiologist reviewed images, aiming to detect and characterize pulmonary, nodal, and skeletal abnormalities. Clinical CT and BH CT were compared for number, size, and location of lesions. Lesion SUVs were compared between clinical PET and BH PET. Images were also visually assessed for accuracy of fusion and registration. RESULTS All patients had lesions on clinical CT and BH CT. Pulmonary BH CT detected more lesions than clinical CT in 13 of 15 patients (86.7%). The total number of lung lesions detected increased from 53 with clinical CT to 82 with BH CT (P<0.001). Eleven patients showed a total of 31 lesions with abnormal (18)F-FDG uptake. BH PET/CT had the advantage of reducing misregistration and permitted a better localization of sites with (18)F-FDG uptake. A higher SUV was noted in 22 of 31 lesions on BH PET compared with clinical PET, with an average increase in SUV of 14%. CONCLUSION BH PET/CT enabled an increased detection and better characterization of thoracic lesions compared with a standard PET/CT protocol, in addition to more precise localization and quantification of the findings. The technique is easy to implement in clinical practice and requires only a minor increase in the examination time.
منابع مشابه
A Comparative Study of 3-D Conformal Radiotherapy Treatment Plans with and Without Deep Inspiration Breath-Hold Technique for Left-Sided Breast Cancer
Introduction: The rate of cardiac diseases have increased among patients who underwent radiotherapy for left-sided breast cancer. The study’s aim was evaluate the dose to organs at risk in free-breathing 3-dimensional conformal (FB-3DCRT) against 3-dimensional conformal deep inspiration breath-hold (3DCRT-DIBH) in patients with left-sided breast cancer. Ma...
متن کاملSingle 20-second acquisition of deep-inspiration breath-hold PET/CT: clinical feasibility for lung cancer.
UNLABELLED This study was designed to compare tumor (18)F-FDG uptake between a single 20-s acquisition of deep-inspiration breath-hold PET/CT and free-breathing PET/CT for lung cancer. METHODS Before the clinical study, a phantom study was performed to determine the optimum breath-hold time for the PET scan. We studied 47 patients with lung cancer who underwent free-breathing PET/CT with the ...
متن کاملA gated deep inspiration breath‐hold radiation therapy technique using a linear position transducer
For patients with thoracic and abdominal lesions, respiration-induced internal organ motion and deformations during radiation therapy are limiting factors for the administration of high radiation dose. To increase the dose to the tumor and to reduce margins, tumor movement during treatment must be minimized. Currently, several types of breath-synchronized systems are in use. These systems inclu...
متن کاملDetection of a liver metastasis by breath-hold FDG-PET/CT not visible on standard PET/CT.
Contrast-enhanced magnetic resonance imaging (ceMRI) was performed in a 62-year-old male patient with a history of colorectal cancer (CRC), with evidence of a 3.0 cm lesion in segment 7 of the liver, near to the diaphragm. To exclude extrahepatic disease a routine PET/CT with 263 MBq F-fluorodeoxyglucose (FDG) was performed in free breathing (fbPET/CT). The liver lesion suspected at MRI was nei...
متن کاملDeep Inspiration Breath Hold [(18)F]FDG PET-CT on 4-rings scanners in evaluating lung lesions: evidences from a phantom and a clinical study.
OBJECTIVE To investigate the clinical feasibility of a Deep Inspiration Breath Hold (DIBH) (18)F-FDG PET-CT acquisition in apnea and compare the results obtained between these acts of acquisition in apnea and in Free Breathing in the evaluation of lung lesions. MATERIAL AND METHODS A pre-clinical phantom study was performed to evaluate the shortest simulated DIBH time according to the minimum...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine
دوره 48 5 شماره
صفحات -
تاریخ انتشار 2007